“Brother’s Little Helper” is the second episode of Season 11 and aired on October 3, 1999. The episode was written by George Meyer and directed by Mark Kirkland. Mark McGwire guest stars as himself.
After Bart continually acts up in school, Principal Skinner recommends to Marge and Homer that Bart take some behavior medication. The drug initially shows promise, but it quickly alters Bart’s psychosis and turns him into a paranoid conspiracy theorist.